Changes to combat (specifically for PC).
If it stays as it is (with whatever updates or tweaks BW feels would add to it), then I'm good. I can deal with the other changes easily enough.
If it approximates the ME method of combat, relying on twitch control skills (i.e. relying on MY ability instead of that of the character I play), then I will pass on this.
I play RPGs for many reasons. Story, characters, dialogue, interesting world to explore and learn about...and the controls do not require me to distract myself from enjoying those things overmuch. I can play at a nice relaxed pace, and let the stats of my character(s) determine how good s/he is at combat, spellcasting, sneaking around, etc. This is why I passed on ME. Action RPGs I simply cannot be bothered with. It's an evolved side-scrolling beat-em-up, with the illusion of stats that mean anything.
Now, all that said, if indeed combat goes the way of ME and I do not purchase DA2, I still wish great success to BW and it's talented people (EA....well, I do not like EA and I will leave it at that).