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Questions about thane's condition/ possible bioware flaw in scientific writing.


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#1
Skirlasvoud

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I managed to hoist this information from the LOTSB expansion:
  • Thane's Medical Report From Dr. Chakwas 
  • Lung Capacity: 42% (left-side lung shows large lesions, right lung has nodular lesions only)
  • Antibiotic treatment: Now resistant to cipoxidin, malanarin, alburcin
  • Metastatic progress: stomach, liver(minor), heart (negligible at this time)
  • Treatment Options: Viable transplant candidate but refused to be added to list Synthetic lung generation currently impossible for drell
  • Therapy and Care: At this time, Mr. Krios should continue getting regular cardiovascular exercise in order to stimulate lung movement and prevent or delay the stiffness that causes lack of oxygen transport. While physical stimulation may also be beneficial in keeping tissue flexible, any injury at this point will dramatically impact Mr. Krios' body and cause rapid degeneration. It is unclear how much longer Thane will be able to serve in direct action. Thane should continue to wear loose clothing that leaves his chest uncovered to prevent moisture buildup that could worsen the problem
 

Combined with information from Wowwiki (reliable enough):

[*]
  • Because the drell ancestors emerged from arid, rocky deserts, the humid, ocean-covered hanar homeworld of Kahje proved tolerable only when the drell stayed inside a climate-controlled dome city. The leading cause of death for drell on Kahje is Kepral's Syndrome, caused by cumulative long-term exposure to a humid climate. This syndrome erodes the ability of drell lungs to take in oxygen, and eventually spreads out to other organs. It is noncommunicable, and there is currently no known cure, though leading hanar scientific authorities are working on creating a genetic adaptation.
As a biomedical student, I'm confused about what the Drell are actually suffering from, because Dr. Hacksaw is proscribing Thane antibiotics.  

Antibiotics don't work on anything other than bacterial life. Virus and Animal cells like those of humans and lizards, whatever Thane is, are completely unaffected by the effects of antibiotics. You only proscribe them to a patient, when he suffers a pathogenic bacteria within the body, whom are vurnerable to them. They might incidentally gain resistance to them, but the patient certainly doesn't.

So is it a condition where the body is ill adapted to the outside enviroments (with evident deterioriation into malignent tumors)? 
Or is it an infection caused by bacterial pathogens that spread and inflict harm on cells?  


It's possible that his infection is a side-effect of already weakened lung tissue through a non-pathogenic condition, but if the infection is so bad that they are already building up a resistance within his lunges, than the bacteria themselves will surely kill Thane before the condition does. Bacteria work fast when the situation favors them and Thane should be deadly ill from the infection alone, not capable of active duty as his body develop fevers to stave off infections to such an important organ as the lungs. At any rate, antibiotics are a treatment to a side effect and shouldn't be mentioned in efforts to contain Kepler's syndrome itself.  

To say that Thane himself is resistant against antibiotics, clearly shows a lack of insight, unless a drell works completely unlike earth life. I'd be dissapointed in Bioware's writing staff if they make the silly mistake to think that antibiotics affect animal life.

With that, I must conclude that Thane's condiction is pathogenic to take still take Bioware seriously. Maybe this is caused by an oppurtunistic bacteria who thrives only when a drell inhabits moist conditions.


However, this makes curing it very easy. The bacteria could be eredicated and Thane be given immunotherapy instead of wait for gene therapy. If these assasins really are that valued, he could be given an antibody regimen to save his life. Give him passive immunity, before the drell can work out a way to arm his active immune system against it, so he can create his own antibodies through gene therapy. The only reason why we can't manage that in 2010, is because gene therapy is beyond our knowledge and innocculation through an antibody regimen is prohibitively difficult and expensive. But it perplexes me that in 2183, the Hanar and the entire scientific council community at that day and age, can't come up with an answer to a simple microbe and synthesize something apropriate when most major diseases have been lain to rest.
And if the bacteria is noncommunible, than how do the Drell contract it at all?

Bioware should either rethink their visions on antibiotics, or rewrite Dr. Hacksaw's report.


I'm also pretty perplexed about the connection between his lung tissue's inability to cope with moist conditions and cancerous metastasis onto other tissue. Kepler's system must develop tumors in Drell. It's very well possible to develop local cancer when tissue is stressed, but Bioware will have to be consistent. We're dealing with Drell Cancer.

Modifié par Skirlasvoud, 17 septembre 2010 - 12:38 .


#2
Guest_Shandepared_*

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Scientific inaccuracies, in my Mass Effect?

#3
Dean_the_Young

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Next thing you know, you'll be telling me that mass effect fields aren't possible either!

#4
Skirlasvoud

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I happen to take Bioware very seriously. :P They've done really well up to this point. As a student of the sciences, I'm not just drawn into the story, I'm also drawn in to what they're doing to explain it.

So yes, I take the time to write things down.


Other than that, I get peeved off when I have to explain people for the tenth time, that humans cannot build up resistances to antibiotics. The bacteria do.

Public awareness of the relation between Antibiotics and Resistant bacteria is getting kinda important these days, if any of you have been following the news. We're heading into a future where we can no longer cure infection and life-spans might plummet by five years as a result, simply because of this ignorance.  

The last thing I need is to be confronted by this ignorance in MY favourite game. :P

Modifié par Skirlasvoud, 17 septembre 2010 - 12:45 .


#5
Killjoy Cutter

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"I have a cold, give me antibiotics!" Grrrrr... some people are so damn stupid.

But yeah, to the OP's point, there seems to be some confusion as to what Thane has... tissue degeneration, cancer, bacterial infection... what?

I best, I could see the antibiotics being preventative, but that seems like sloppy work for a highly skilled doctor.

Modifié par Killjoy Cutter, 17 septembre 2010 - 01:15 .


#6
Guest_Shandepared_*

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Skirlasvoud wrote...

I happen to take Bioware very seriously. :P


Well that's your first mistake.

Mass Effect is great, it is some nice science fiction. Emphasis on the fiction. Almost nothing in Mass Effect makes sense upon closer scrutiny.

Element zero and mass effect fields are basically just magic handwavium. Same with biotics.

It's all done pretty well though, so I don't mind.

#7
Tazzmission

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Shandepared wrote...

Skirlasvoud wrote...

I happen to take Bioware very seriously. :P


Well that's your first mistake.

Mass Effect is great, it is some nice science fiction. Emphasis on the fiction. Almost nothing in Mass Effect makes sense upon closer scrutiny.

Element zero and mass effect fields are basically just magic handwavium. Same with biotics.

It's all done pretty well though, so I don't mind.





bitocs is a real possibilty for us to have sooner rather than later. look at darth vader for starters what is the suit for? its basicly a giant iron lung and yet we have iron lungs for people who need em. just because something seems impossible to cheive dosent mean it is.

#8
Guest_Shandepared_*

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Tazzmission wrote...

bitocs is a real possibilty for us to have sooner rather than later.


I don't how to respond to this.

#9
stewie1974

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biotics is schlock science.... mass effect fields is schlock science... show me proof otherwise.

#10
PsyrenY

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Skirlasvoud wrote...

I happen to take Bioware very seriously.


SERIOUS.

:mellow:

#11
Itkovian

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BioTICS, not BioNICS.

So, no, there won't be biotics anytime soon. :)

Itkovian

#12
Wildecker

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I think Mr. Tazzmission may have mistaken bionics for biotics.

EDIT: Beaten by seconds ... :o

Modifié par Wildecker, 17 septembre 2010 - 01:45 .


#13
FlyinElk212

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o.o

CHAKWAS IS AN ANAGRAM OF HACKSAW!!!!!!

*knows what to put in the "D'oh! Moments" thread*

#14
Whatever42

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I suspect its a treatment for an accompanying condition to the syndrome. That the doctors notes don't mention it could simply mean that its a standard condition.



My brother is an RN and has often complained about the poor charting of doctors and his co-workers.

#15
Christmas Ape

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Wait....hang on. This isn't a textbook?





...does this mean I have to scrap my Conduit prototype?

#16
Exile Isan

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Because of the deterioration of his lungs he may be more susceptible to bacterial infection, perhaps that is why the Doc was prescribing antiboitics. Just guessing. I've always thought of Keprals Syndrome as like drell version of Tuberculosis which I'm sure is inaccurate but hey.

Modifié par Exile Isan, 17 septembre 2010 - 11:44 .


#17
Skyblade012

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In the Codex, Kepler's Syndrome is described as a bacterial infection. When you speak to Thane, he describes it as an inability for his arid-born species to properly handle water (yet they still cry like a human does...).

#18
Exile Isan

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Skyblade012 wrote...

In the Codex, Kepler's Syndrome is described as a bacterial infection. When you speak to Thane, he describes it as an inability for his arid-born species to properly handle water (yet they still cry like a human does...).

I thought Thane said the drell's lungs couldn't handle all the moisture/humidity of Kahjee's atmosphere?

#19
MrnDvlDg161

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I can find plenty of bad science.

At some point...you really do need to step back and look at it for what it is then searching for things that it   isn't meant to be.

Modifié par MrnDvlDg161, 17 septembre 2010 - 11:55 .


#20
Eradyn

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Considering BW's history in medicine, it is odd that THIS would be something (potentially) in error. Hopefully some light can be shed on the matter...but if not, I guess it won't ultimately change whatever they are going to do.

#21
Axelom

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Actually, if Kepler's syndrome erodes the ability of drell lungs to take in oxygen why don't they just replace them with artificial lungs? Considering we have pacemakers TODAY, it should be a cakewalk to give the patient a new pair of lungs by 2183.

#22
JBPBRC

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^ Thane refuses to get lung transplants because....well, because.