Bogsnot1 wrote...
aeetos21 wrote...
Finally, favorite potential non-squadmate (past or present) encounter I'm looking forward to potentially seeing would be between Udina and Urz, see a varren pissing on Udina's shoes? Priceless 
With Boo taking a crap in his sandwich as well. 
"Where goes the stench of evil, so goes the cleansing turds of Minsc and Boo!" *Boo squeaks*"Every Hamster, HAS his day!" *Boo squeaks*Anyway, on-topic, Renegade Shep having a fight with Samara and making it so she finally finds peace in the embrace of her goddess herself >

yeah I know could kill her in ME2, but it has me intrigued as to whether Bioware will go through with what she said... potential squaddy for Paragons, potential enemy for Renegades, BRING IT ON SAMARA! Soon you will be scoped and dropped

Seeing a difference with the Quarians depending on whether you handed the evidence over during Tali's trial or got her exiled or did one of the other things that got her cleared without troubles brewing for them. Also seeing how they react to you if you didn't recruit Tali or didn't take her to the trial. So many variables just for this instance

My 'Worse playthrough' Shep (only an unloyal Kasumi/Zaeed alive with Joker and lots of bad decisions made on loyalty missions or just not done at all) having downright impossible chances of gaining allies due to messing things up in the previous 2 games. Please Bioware, show that you got the quads to do this, I want that playthrough of ME3 to be downright hard to complete without major trouble.
Cerberus Loyalist Shep getting the opportunity to kill Anderson
Anti-Cerberus Shep getting the opportunity to kill TIM AND Kai Leng... or at least letting Aria do the latter
Speaking of Aria... Aria vs Wrex the re-match, or in Paragon case stopping them from doing so to ensure they both help fight the Reapers

'Big Ben' Marine being rescued just before Big Ben and the Houses of Parliament are completely destroyed but only after we've had a fight with the Reapers ground troops inside said buildings with the layout being accurate with minimal 'futurisitic' updating of the insides. Ok... I know that ain't going to happen, but I can dream can't I

Khalisah Al-Jilaini getting killed by Keeper 20 after she stupidly tried to interfere with its work.
Citadel facing an influx of Krogan looking to make it to the Presidium for the glorious fish it supposedly has for any Sheps who lied to that Krogan in ME2

As a side effect though, shops on the Citadel now won't offer any pets to anyone who did this.
Said Krogan complaining to some C-Sec officer that there should be fish in the Presidium lakes if he was told by Shep in ME2 the truth.
Shop owners on Citadel refusing to give Paragon Sheps a discount due to rumours of them making false claims about each store being their favourite on the Citadel

(I have a Paragon Shep who does this and I would actually find it funny if this happened).
John Whitson (silly kid wanting to play 'Merc' on Omega on garrus recruitment mission) now running a store on Omega and automatically gives Shep a discount for saving his butt.
Meeting Seryna (spelling?) somewhere and if Thane is with us and we read the message she offers to buy us a drink as she said she would for Thane. That has me wondering as just realised I've never took the 'Delete Recording' option, might try that in next playthrough to see if anything significant happens as seems odd there is a choice there.
Niftu Cal having a store somewhere and remembering us for saving him from making a fool of himself and getting himself killed.
Shepard getting to meet whomever was the Krogan who wanted to breed with them after Grunt's loyalty mission

Just a few I can think of right now.