From what I've seen on the forums and the intertubes at large, it's considered pretty "Forever Alone" to put much interest or effort into the love interests in DA and ME. Many people apparently wish Bioware would take them out completely and focus on the stabbing darkspawn aspects. But I must confess, the romantic subplots are part of the games that I really enjoy and that I think sets the series' apart from standard (that is, non-Bioware) RPGs. Romantic love is part of the human condition, a huge, integral, all-consuming part, actually. Just yesterday, many of us celebrated an entire holiday based around the concept. Adding that element to a game is just one more step toward the video game experiences becoming fully realized stories, rather than simply a series of tasks or fights or achievments.
With that said, I am a bit disappointed with the (apparent) romantic attachments announced for DA2. In both ME and DA I have played female lesbian characters. I thought Liara was amazing in ME1 and ME2 Shadow Broker DLC (though I chaffed at all the simpering on whether it really counted as a same-sex relationship.) I also really liked Tali and found it a bit annoying that she was a F/F love interest that was intentionally removed, despite the presence of completed audio files. It seemed like a weak-kneed response to the Fox News controversy from the first game. But then there was Leliana in DAO who was also wonderfully realized. She was really quite a break-out from the same-sex stereotypes, she was mostly chaste (her past notwithstanding) and highly religious. Not only that, she was sweet, caring, and had an unbeliveably sexy accent.
But if Isabella is truly the bi-female option in DA2...I think my Hawke will remain herself forever alone. I would imagine gay men felt the same way about Zevran in Origins. He was a great character and quite a cool addition to the party. But I couldn't help but think his constant hitting on other characters (primarily the female party members)would become annoying if a male Warden was in a same-sex romance with him. That, to me, is more game-breaking than having a party of four potential bisexual love-interests. Which wouldn't be a problem if the gay male Warden had other options beyond Zevran. You want the flighty guy who may be romancing any number of bar wenches behind your back? Sure! You want character Male character B who is more romantic, loyal, or simply different? That's fine too. Opposite sex characters had that romantic choice, same-sex ones did not.
Isabella (and, again, this is all purely speculation still) seems to be on track for a similar role as Zevran, and that's simply not appealing to me. Now, surely anything can happen. Perhaps the character is so well written and portrayed that there is far more depth to her than simply a sex-crazed, untrustworthy pirate. But I was, and to a lesser degree still, hope Merrill will turn out to be a FemHawke LI as well. But even if that's not the case, I can't complain too much. As I said, Liara and Leliana were just wonderful characters and I really enjoyed and appreciated their romantic subplots, even if that does make me one of "those" gamers.