Zelnik wrote...
These are mostly focused on biology, since that is my feild of study, but some of these make me think the writers really did not even consider checking their sources.
1. Humanity has great genetic diversity.
This is not only false, but grossly false. Of all of the primapes on the planet, we are the LEAST genetically diverse. We are more closely related to a member of the opposite gender on the other side of the planet, then a chimpanzee is related to it's sibling. Humanity suffered a massive genetic bottleneck some 50,000 years ago (probably due to Mt. Toba exploding), and the results are extremely clear today. The huge amounts of cancers and genetic disorders found in humanity are the best example of this.
2. A weak Immune system involves fevers, allergic reactions, etc.
This assumption is actually a bit backwards. If an organism has a STRONG immune system (or hyperactive immune system), the above examples occur. A WEAK immune system would have no reaction at all to a foreign pathogen, and the only sign of illness would probably be death, or necrosis. All of the Quarian examples of "weak immune system" make any medical professional very confused (I know, I am one, and so is my father). The described reactions show more of a hyperactive allergic response.
3. Eating Dexter compounds is a BAD THING!
Splenda would like a word with you. Yes, it's true that you can develop a response against it, but allrgies to Dextrose are rare, but its MUCH more common for it to just pass through your system. I understand the hypersensitivity for the quarians, but Turians would probably just have the runs for a while.
4. Dextro-Amino acids could KILL YOU!!!!
Similar to 3, but any immunologist would tell you that this is extremely unlikely. When protiens hit our gut, they are broken down into their individual amino acids (this is assuming our proteases work on dextro-amino-acids). amino acids are TERRIBLE antigens, since their molecular weight is so small. Odds are they would not even be absorbed by the intestinal mucosa.
IF they were NOT broken down by the proteases, the HCL would denature the protien chains, though it would be more likely that these could yeild an immune response (though this is also unlikely, since they probably won't pass through the intestinal mucosa either.
5. You can walk outside in a vaccum with skin exposed.
This should be pretty damn obvious. If a shield breaks down due to radiation from a hot star, why isn't it breaking down from temperatures around 4 Kelvin?
6. Aliens look just like us.
Seriously.. must everything in science fiction have four limbs, two eyes, one nose, boobs, and...oooo blue skin.. 
I don't know what I find more funny the fact this is based on strictly human biology or the fact parts are missing. I am a Scifi author for a living and something I learned from experience. Science cannot prove what cannot work only what can. So 1 that blows number 5 4 and 3 right out of the water. We have never met another Sapient Amino Dextro life form from a different planet. Nor do we know 100% what the reactions would be like in an alien life forms immune system. We can only predict. Yes number 5 annoyed me Until I broke it down heavily. EAch time someone was in exposed vaccum there were mass effect fields around. Also the suits shields are mini mass effect fields or kinetic barriers. Since neither exist we must leave it to the Authors to tell us what the Field does. And if anyone refences the Opening cutscene with joker look in ME1 where the hatch is. As for the Brown dwarf you weren't in a vaccum the rest you just need to look harder.
I know I'm going to get flak for this so don't bother trying to get me to argue I won't.
As for the Alien forms we have no idea what a sapient life form from another planet would look like since the closet the that we have found is bacteria. And that looked pretty similar. Or would you prefer to romance a preditor and HR Giegers Alien?
NExt 3 is based on simply what humans are like now and the rest of life forms. But it is made very clear humans are nothing like this in ME several times we are told about how common Gene mods are and body reconstruction.
Saying any dextro acid will kill you is like saying orange juice can rid a corpse. This is once again based on EARTH. if the game took place on Earth that would be legit but its not so how would we know what could and couldn't happen in real life? since these are from different planets and eco systems. Plus Tali does a pretty good description of why her immune system causes those side effects. That is also since no life form that is sapient and intelligent has been found with the Quarian gene make up.
Now am I saying your 100% wrong no but your making a pointless comment because will it get people to stop playing its a game. Same as frankenstien its as false as possible but thats why its called Suspension of Disbelief
Also If you pay attention each alien is based of an Earth animal.
Humans: monkeys
Turians: Chickens
Salarians: Salamanders
Asari the three above mixed
Elcor: Elephants
you get the picture
Also Evolution may be near proven but what we evolved from is still pure speculation
AS for the most genetically diverse
Well I haven't seen the Gene structure of any other race so you can't really make that statement because you don't know. Plus Need I say it again Gene mods and Human mutations as well as adaptiions that could have modified the Gene structure.
as for 3 we don't know the compound but they already state not to ingest and once again your basing your assumtion on our planet being the only one with life
Yes I know there are spelling errors and typos mostly cause I don't feel like editing it.
I know people are going to try to pick a fight and I say I don't really care.
No I am not mad or upset
I am just pointing out how silly these arguments can get.
Also since the Mass effect fields seem to be the "Force" of ME aka the dues ex machina to make things work. you have to remember to toss things in using it. Probably the difference between a scientist and an author, is Authors are willing to have fun and be less strict.
Now if this were a Scifi like the game Singularity which doesn't even try to do its homework. Then I could understand. If anyone doesn't know what I am talking about ask a person who knows chemistry if the molecule would be named after the year. aka E-99