Well, everybody. Someone over at GameFAQs got their hands on the issue already, and apparently, they've scanned some information out of it.
Confirmed Characters
Namely,
Ashley Williams, Kaidan Alenko, Liara T'Soni, Garrus Vakarian, and a new character named James Sanders are confirmed to be playable. Mordin Solus, Legion, David Anderson, and Urdnot Wrex are confirmed to be in the game, but their playability is unknown. The Illusive Man and Donnel Udina are also confirmed to return.
Husks aren't just human anymore.
Also, the article confirms some interesting features.
The RPG elements are being beefed up, not going back to ME1, but giving more freedom with the character skills. Skill trees will be larger, and powers will evolve several times instead of just once, offering even more freedom. Weapons are ME2 style, with a set list, but mods make a return, not in the ME1 style, but allowing you to swap out different parts such as barrels, scopes, and so on, which effect both the weapon's combat performance and its appearance.
All classes can wield all weapons unhindered now, but will have limited slots to carry them. Only the Soldier can carry all weapons at once. Probably means Adept, Engineer, and Sentinel will be limited to two, and Vanguard and Infiltrator will have three.
Also mentioned: The game will have numerous endings, some good, some bad, and who you have in your squad and which allies you recruit can have a drastic effect on which are available.
Oh yeah, forgot to mention one thing: Confirmed NO MULTIPLAYER. They're talking about future games and/or spinoffs having it, but not this time.