The only time they can break free is when a Reaper chooses to abandon their thrall, or if their will hasn't been completely subjugated, suicide.
Paul Grayson from the Books is an example of the Former, The Reapers left him when his body was critically damaged before he was shot in the head.
TIM and Saren are examples of the latter, they had will enough to shoot themselves before things got worse.
Shiala is unique, she was indoctrinated, but thanks to the presense of Thorian hive-mind spores in her and the Zul's Hope colonists, they were aware of the fact and able to fight against it effectively, possibly by listening to the voices of their fellow colonists rather than the Reaper. I'm not entirely certain how that would work...
Shepard's brain has been altered on a fundimental level thanks to the Beacons and the Cipher, he may become indoctrinated, but it will take a lot of effort on the part of the Reapers and probably would never be fully complete.
Modifié par Aurora313, 06 juin 2012 - 10:12 .