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Thane Thread 'It's difficult. All things worth keeping are.' Spoilers will be neck-snapped.


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#126
wildannie

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@gnas That's exactly why I think the development of a treatment is perfectly plausible. Drell seem to be quite rare, the research into a cure is being carried out by the Hanar and we really do not know how skilled they are (not very by the looks of things).
We don't even know if the other races have even tried to find a cure, thane gets pretty shirty when shep asks if they can help, maybe it's not been really looked at by the Salarians, and all that's needed is a well respected scientist salarian to put in a good word somewhere.

Or, maybe Mordin's been working on a cure in his lunch hour and will just produce it after dinner one day :)

edit: top of page... well Thane's in it.

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Modifié par wildannie, 16 juin 2011 - 03:51 .


#127
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@Fiery All the information we have is incomplete. It's part of two of three.

#128
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I agree with Gnas. They are overly simplifying and equating two things that are very different when it comes to the treatment. The causes are different therefore the treatment should be also. And he said he wrote the SB dossier based on that CF disease. So he is saying they are similar.

But I have to say that I always thought they would use Thane as a sign of hope for anyone with any kind of terminal illness (which means cure him) rather than an allegory for ‘there’s no hope for you even in the future, you’re gonna die, ha ha ha’.

#129
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@Wildannie Yes! I agree with your statements. A viable treatment option that takes into consideration the information that has been provided and based in some level of plausible truth, then the game will be enjoyable.

#130
wildannie

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51ha wrote...

I agree with Gnas. They are overly simplifying and equating two things that are very different when it comes to the treatment. The causes are different therefore the treatment should be also. And he said he wrote the SB dossier based on that CF disease. So he is saying they are similar.

But I have to say that I always thought they would use Thane as a sign of hope for anyone with any kind of terminal illness (which means cure him) rather than an allegory for ‘there’s no hope for you even in the future, you’re gonna die, ha ha ha’.


I'm all for this

#131
Fiery Phoenix

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Gnas wrote...

@Fiery All the information we have is incomplete. It's part of two of three.

So it may not make too much sense yet. I am almost certain Kepral's is to be further looked into come ME3, and you can mark my words on it. At this point, it's anyone's guess to say what is what.

#132
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@51ha Thank you. You are my new hero. :)

#133
Raiil

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I'm pretty sure I noted in my post that it was similar to TB, but specifically mentioned that Kepral's isn't airbourne. I'm not trying to make a perfect analogy.

One of the problems with your argument, Gnas, is that you're arguing on the biology of the drell race when our knowledge of it is very, very scarce. We know that they have denser ,muscle tissue than humans, a hyoid bone in their throat, and a small handful of other information. You keep speaking about having to take immunosuppressants, which I agree would be a huge issue in our current timeframe (current means yours and mine), but this is centuries in the future, with an entirely different race who is not biologically identical to ours where medicine is much more advanced than it is now. Throwing out what we know how about human healing and such has minimal impact in a universe where most diseases have been eradicated. It's a different kettle of fish.

#134
Fiery Phoenix

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On a slightly unrelated note, I find the idea of using Thane as a sign of hope and inspiration to be nothing short of fascinating. I certainly hope that's where BioWare is heading.

Modifié par Fiery Phoenix, 16 juin 2011 - 03:29 .


#135
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@Fiery Actually I am not going mark any of the writers words simple because I want to see how they are going to pull the issue of Keprals syndrome and a plausible disease out of the preverbal toilet. In my opinion, they did not do a very well thought out job on the disease. And the writers changed so, it is yet to be seen or known.

#136
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@Valentia again, plausible truth in order for some suspension of disbelief to occur. In my opinion, the error occurred in the comparison of CF with Keprals in the first place. Yes there are similar symptoms but as you pointed out, human physiology versus drell physiology. Yet, there are simple basic knowledge we can apply what we do know with the unknown. Being that Keprals is an infection thus warranting treatment with antibiotics

When you get into reality based diseases like CF, it's more complex and comparing it to a fictional disease lessens the impact and reality of that disease. Not to say the personal toll dealing with a similar situation that can incur. Then it comes down to an individuals personal situation and should be taken from that perspective.

#137
wildannie

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@gnas cure is far and away my preferred outcome. I can settle for a lung transplant although I would find a new drug treatment or cure more plausible.

I do think that this cure should happen in sheps absence as once the reapers arrive it would seem unlikely that anyone would devoting time to a Keprals cure research.

I favour that Thane is cured for ME3, no fuss, just cured... unless you **** up his loyalty, in which case he's dead or dying.

#138
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@wildannie viable treatment option, I can see as a plausible outcome. There needs to be more information in order to salvage Keprals from an infection to a genetic disorder, if they can pull that off, then the option of a lung transplant will make sense. But without that additional information, it makes it difficult to see why it would work.

#139
wildannie

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Gnas wrote...

@wildannie viable treatment option, I can see as a plausible outcome. There needs to be more information in order to salvage Keprals from an infection to a genetic disorder, if they can pull that off, then the option of a lung transplant will make sense. But without that additional information, it makes it difficult to see why it would work.


Is there a genetic aspect to Keprals? it's not communicable so does a drells genes determine whether they will develop the disease?  

#140
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@wildanne Thane himself says its noncommunicable. Now, genetics versus immunology, there in lies the crux. If, IF, like CF, they were treating the infection that is occurring due to the underlying genetic condition, then the use of an antibiotic makes sense. BUT, why haven't the Hanar been able to determine Keprals is a genetic disorder? More information is needed.

#141
wildannie

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Gnas wrote...

@wildanne Thane himself says its noncommunicable. Now, genetics versus immunology, there in lies the crux. If, IF, like CF, they were treating the infection that is occurring due to the underlying genetic condition, then the use of an antibiotic makes sense. BUT, why haven't the Hanar been able to determine Keprals is a genetic disorder? More information is needed.


because they're big jellyfish :D

#142
Raiil

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IIRC there's no genetic predisposition or factor known to contribute to having Keprals, other than the obvious drell thing.

As far as I can tell, the process seems to be drell is exposed to continously humid, rainy ecosystem --> either the wetness or some sort of bacterial/fungal component in Kahje settles in their lungs --> breakdown of lungs begin --> after some unspecified amount of time, Kepral's begins to spread to other body parts --> degradation continues until death

The lung transplant, as far as I can tell, would simply reboot the process after initial exposure, but before the breakdown begins. So it wouldn't qualify as a cure, rather as an temporary stopgap; the codex mentions that eventually, even transplants have diminishing returns and aren't going to stop Keprals, only delay the inenivtable.

#143
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@Wildanne LOL very true. :) Where are the salaries when you need them?

#144
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@Valentia Eureka! Because transplant are not treating the underlying cause. If it is a genetic disorder, then some advance technology for genetic therapy would be needed. IF it is genetic that is. But what if it's a specific bacteria? What if it's the Drells immune system? What if... Bah, there are too many what if's.

#145
Raiil

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I never said they were treating the underlying cause :/ I've actually been a bit of a motormouth (not here, other places) that the lung transplant isn't the cure, just a bandage with an experation date :P

Honest guess? I doubt it's genetic; I always read the 'genetic' aspect of the hanar cure as an attempt to simply modify drell genetics into having more moisture AND bacterial resistant lungs. Keprals, to me, seems more like a perfect storm situation where there are several aspects that play into causing Kepral's in the first place. A type of bacteria/fungus specific to worlds more waterlogged than Rahkana (re: just about all of them), lungs unable to withstand great humidity, thus making them more susceptible to hosting bacteria/fungus, an immune system that hasn't had time to adapt or learn to fight back against foreign disease (like when the conquistadors brought over all manner of diseases to the South Americans). It's not just the one thing.

#146
Sister Helen

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... Seeing as how Reapers think humans are the best thing to make Reaper offspring with, it might be that humans as a species (and Shep in particular) might be easier to treat/cure/ recover from almost-death than drell.

... Don't drell in general have shorter lifespans? If humans live about 125 years and drell only 85, it may be that the drell genetic material just doesn't last as long as human material. Or disease and the normal course of aging is accelerated in comparison to humans.

... I guess I just figured Thane was in his mid-50s or early-60s, based on his retiring from hanar service and having a kid of Kolyat's age.

#147
Raiil

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Thane's 39, so he's about at the middle-age mark.

Since so much of why humans live longer seem to be attached to modern medicine/genetic manipulation and modification, I'm not sure if humans are 'stronger' or just the beneficiaries of a system that constantly looks to improve humanity. The drell were pulled from the brink of extinction and a possible total-war event; they just might not have bothered to develop the same medical tech since right now, they're probably just focused on not dying from Kepral's and possibly repopulating.

Or I'm somehow channeling Guns, Germs, and Steel and just not remembering.

Modifié par Valentia X, 16 juin 2011 - 04:10 .


#148
wildannie

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Sister Helen wrote...

... Seeing as how Reapers think humans are the best thing to make Reaper offspring with, it might be that humans as a species (and Shep in particular) might be easier to treat/cure/ recover from almost-death than drell.

... Don't drell in general have shorter lifespans? If humans live about 125 years and drell only 85, it may be that the drell genetic material just doesn't last as long as human material. Or disease and the normal course of aging is accelerated in comparison to humans.

... I guess I just figured Thane was in his mid-50s or early-60s, based on his retiring from hanar service and having a kid of Kolyat's age.


yeah, but he started training when he was six and killed his first mark age 12...  I think he's early 40's 

I thought that the reapers interest in humans stemmed from Shepards role in the destruction of Sovereign.  Mordin does say something about humans being good test subjects as they varied alot, don't know if that's relevant to this or not.

edit: oh so he's 39, I missed that.

Modifié par wildannie, 16 juin 2011 - 04:13 .


#149
Fiery Phoenix

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Yeah, Thane is only 39. Not even halfway through the average drell lifespan of 85.

#150
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Thane is a classy dude. I'm looking forward to seeing how Bioware resolves his story.