Didn't really dislike him, but was bored with him. My reasons:
On my first playthrough, I picked female Shepard. She liked Jacob instantly, he was nice to her at the beginning, and he wanted her to trust him, which was sweet. Then we're on the ship, and she decides to talk to Jacob...
The words that came out of her mouth made me shudder. The tone of her voice...ugh. That very moment I decided that there will be NO romance. But we can still be friends, right?
But no. For some reason, Jacob, who seemingly had no problem with me, is constantly very rude to me out of blue. At some point, it occurred to me that I don't HAVE to talk to him. At some point later, it occurred to me that I don't even have to take him on any of the missions. After that, I pretty much erased him out of my mind.
Even Zaeed, a cold-blooded killer, knows how to get rid of Shepard without insulting him. Why can't Jacob inform me that he has no new conversations without being so insulting about it? Well, if you don't want to talk, we won't talk. Ever.
And then, he has a pretty horrifying loyalty mission, and he's so utterly unshaken about it. I get it that he doesn't want to dwell on it, I do. But it came across like he was walling off Shepard, and didn't trust her at all to open up to her. And really, emerging out of something like that unscathed, he's just way to perfect for my liking. Invulnerable is boring.
What shakes him? What drives him? What is his greatest fear? What is his greatest desire? I can't get a feel of his character. He's simply...not there. Granted, Samara was much worse. She was practically nonexistent. But at least she had a purpose.
And he had a lovely moment with Tali, when he greets her and she throws a temper tantrum like a little princess about having to work on this horrible ship with these horrible people, and she'd gladly use a grenade on all this horrible stuff. And then he tells her to introduce herself to the ship's new AI.

Meaning, girl, this ship is much more horrible than you had thought. She was rendered speechless at that moment. Must have realized that if she continued with the insults, she'd have no reason whatsoever to stay on this ship - the worst possible place in the galaxy. She talked herself into a corner, there. Priceless how he handled her without a word of insult.
But I can't remember any more memorable moments with him. Oh, but wait. There's one, where he tells Shepard that she's the perfect example of humanity.