I don't know what has brought TIM to using the brute force "research" the remnants of which we come across all too often in the game, but I can get behind this manifesto 100%.
I honestly think that this is because, despite TIM's desire to see humanity rise in general, his regard for individual life is pretty much nil. Everyone is expendable in the name of seeing his vision brought about. The only time he's upset over death is if he loses an asset too soon for his liking.
I hope when we meet TIM again in ME3, something of the man who wrote it is left.
I don't think he needed to change at all. If you mean "the man who wrote things like 'it is with a heavy heart' and actually meant it," I don't think he ever existed.
It is interesting to see, btw, how this is not so much about human dominance than about survival. Harper/TIM knew about the existence of something like the Reapers all along, and protection against this threat is his main concern. The second-but-last paragraph also sounds like an agenda of enlightenment, which I support against the perception of the universe as a place containing inherently incomprehensible Cthulhu-esque monstrosities.
TIM is casting a wide net. He doesn't just want to have speciesist dicks being recruited; Cerberus' standards are rather high and he doesn't want to limit the application pool, as well as trying to grab ex-Alliance members for the sake of intel and other reasons. For his actual agenda, the only time I feel he's not being a politician speaking with carefully controlled words is in the Paragon ending, and that's where he breaks out "secured human dominance against the Reapers
and beyond," (emphasis mine) and "Cerberus is humanity."
In character: You're delusional.
How odd. I thought that required a disconnection with reality instead of recognizing the patterns leading to my victory.