I've been gaming since the 70's. Yes I am that old.
I'm a female, but Mass Effect is the first game ever that I used a female character. I almost always use a male character, if given a choice. Some games don't give you one.
I tried using Sheploo on my first time playing, It was a rental and I didn't enjoy playing with Meers boring acting. Yes, Meer made me not care about maleShep. I ended up returning the game without getting through Eden Prime. Several months later, I was at Gamestop just looking around. I noticed ME was under $20, so I decided to try it again. This time with femShep. I fell in love with the game quickly.
Now, I have forced myself to play maleShep to see all the romances. I play more femShep than anything and my canon femShep the most. Five playthroughs on ME and eleven on ME2.
Still to this day, I usually play a male character over a female one. I did it with both Fable II and III. Fallout 3 and New Vegas.
Because BioWare does such a great job with female leads, I've played more femHawke than male even though both VA did a good job. Wish I could say that with ME.