What I'd like to see happen is for the ending to play out as it is. Your LI gets out of the crashed Normandy...then turns to the camera and says "Shepard! Shepard get up!" Then BOOM! You're in London. Harbinger is firing his giant laser at you. Your LI is there, dragging you to your feet. Suddenly, the Normandy is there, Joker at the helm, attacking Harbinger, giving you the time you need to reach the Conduit.
If you have an ME2 save with a living Jack and set the students to support roles, they show up and create a barrier around you and your team. A squad of angry Krogan also show up (again, depending on your choices) to clear a path to the Conduit. You and your squad make a run for the Conduit along with any living squad members who were on Earth with you. You reach the Conduit and make it to the Citadel. If you made certain choices, some of your squad and friends will die as you run for the Citadel.
From there it's a straight up fight through the Citadel to reach the Catalyst with you dividing your team up to take on different paths. The way I see it, there's no point in adding DLC for the ending if there isn't going to be any proper gameplay. Fighting your way through the Citadel would fulfill that role.
As you make your way towards the Catalyst, you hear Harbinger taunting you, its taunts being based on the RGB decision you made in the "ending." Unlike most, I wouldn't just have an extended ending be attached to the "Destroy" ending. Nobody should be stuck with basically destroying the galaxy, whatever ending they chose. However the ending you chose would affect what happens in the "real" ending.
When you reach the Catalyst, things would seem eerily familiar. Once again, you'd come face to face with Illusive Man. You can even make him shoot himself in the head again. Or at least you can try...this time around you hear that immortal line "Assuming Direct Control" and it would no longer be Illusive Man standing before you, but Harbinger. The conversation you have with Harbinger would depend on the choice you made while being indoctrinated. If you managed to convince Illusive Man of his indoctrination the first time around, you can try to get through to him, try to get him to break Harbinger's control over him.
Ultimately, Harbinger makes his case for the continuation of the Reapers, again, the conversation is eerily familiar. But this time Shepard is thinking clearly and is capable of countering Harbinger's argument, again depending on the various choices you've made throughout the games (Quarrian and Geth unification etc).
And here's the kicker - you get the same three choices. Well...variations. "Control" becomes a way to not just control the Reapers, but to make humanity the dominant species. Harbinger promises to share Reaper knowledge and technology and give the human race the power to control the galaxy. If Shepard destroys the Geth, Harbinger will recognise Shepard's ability to halt the AI "menace" and humanity will be tasked with keeping the other races in line, deploying Reapers as they see fit.
Synthesis becomes a situation where the galactic races are all harvested to become Reapers, implying that Harbinger has managed to convince Shepard that the Reapers are necessary and that the cycle has to continue.
Destroy simply means destroying all Reapers and ending the cycle. Not all synthetics are destroyed and the Mass Relays are intact. However Harbinger suggests that if the Reapers are destroyed, the Synthetics will turn on the Organics and wipe them out. In fact "Destroy" isn't really an option that Harbinger presents. It's one you decide for yourself and if you choose it, the Reapers will attack the Crucible in order to prevent it happening. This is where all of your war assets and choices come into play. You can choose to destroy the Reapers and you can fail if you don't have the required assets to hold off the Reapers while the Crucible prepares to fire. You can also succeed but the damage will be so great that the Citadel and Crucible will fall out of the sky, obviously killing Shepard and his squad. Also, Harbinger, in Illusive Man's body, will attack you.
There may even be a scenario where Joker will sacrifice himself to defeat the Harbinger Reaper or maybe even EDI will sacrifice herself for the sake of all lifeforms.
Those final moments will depend entirely on the choices you've made across the trilogy. Who lives and who dies, who comes to your aid and who doesn't. Available weapons and troops, the right people in the right places.
In most of the "Destroy" scenarios, Shepard dies. How he dies depends on how you've played through the games. It's possible to get a happy ending where everyone lives but you have to work hard to get it.
So how does the game actually end?
If you choose to control the Reapers and by extension, the galaxy, the Reapers withdraw from Earth and we see a montage that shows humanity assuming it's new dominant position in the galaxy. Humanity praises Shepard while the rest of the galaxy curses him. Some of your friends, mostly aliens but some humans as well, will abandon you, including your LI (if they would disagree with your decision...Liara, Garrus etc).
If you choose to become a Reaper, you will see a montage of events across the galaxy that show people being harvested, including your friends. More Reapers will jump into the Sol System to take care of the fleet. Earth will be preserved for the next cycle. The game will end 50,000 years in the future with a being from the next cycle discovering Liara's "beacon," implying that it's all about to start again.
If you choose to destroy the Reapers, you can fail and you will see the Reapers being victorious across the galaxy. If you succeed, the Relays will be used to send an energy pulse across the galaxy that destroys them. Reapers fall out of the sky, those people who survive breath a sigh of relief. The Citadel itself may be destroyed, taking Shepard and co with it, or Shepard himself will be the only one to die. In the best ending, Shepard lives.
Whatever Shepard's fate, if you are successful in destroying the Reapers, you will hear Liara's entry about Shepard from her beacon as we see the rebuilding process slowly beginning. We see the fate of Shepard's friends. If Shepard is alive, we see him/her with their LI. If Shepard is dead, we see the LI at his/her grave. Either way, we get a final shot of Earth as the sun sets behind it and we catch a final glimpse of the trademarked Mass Effect horizon line.