Since this isn't a serious discussion thread I don't expect any serious responses to this.
I played ME1, 2, and 3 with MShep and FemShep. Many, many playthroughs with MShep and 1 with Femshep that I carried all the way through.
I though that hands down Femshep was better than Mshep in ME1. She was more consistent, she was more emotive, she was more believable. MShep on the other hand was all over the place, ranging from Badass to I Can't Believe They Didn't Do Another Take. It got distracting and I ended up skipping most of his worst lines.
Things changed in ME2 however. Femshep, and by extension of course Jennifer Hale, sounded like she was trying too hard to sound threatening and badass. The deep, husky tones introduced in the second game in my opinion cheapened her character. Now lines that should sound like a normal person saying a normal thing sounds instead like a person who's trying so hard to be intimidating that they come off as phony.
MShep, and by extension Mark Meer, got significantly more consistent and his lines sounded less and less like a guy trying to act tough and more like a guy who is tough. His "soft" dialog, anything paragon or with crew, sounded more sincere.
However there were still parts of ME2 that I skip through because they still sound terrible.
Now ME3 comes along and Jennifer Hale drops some of her phony-sounding attempts at badassery, but not all of it, and Meer puts on his A game.
The consistency from both VA's was really impressive and Meer's "bad" lines are basically just slightly flat sounding, instead of his previous sick/nasally/creepery/off-tone stuff from the previous two games. Hale was also consistently good, but she never really struggled with consistency like Meer did.
All in all, you have to be a VA connoisseur to pick one or the other because of it. There are better reasons to like one or the other that ultimately fall squarely in the "Subjective Assessment" category.