Oh god, my mind was just blown.
I checked to see if I still had the Cronos station save and just ran through the Normandy and talked to a few people. I had the dialogue with EDI about the prisoners that sacrificed themselves and how she'd rather die than be reprogrammed. At one point, Shepard turns around to look at her and asks "Are you saying that submission would be preferable to extinction?"
Does that remind you of something?
No?
Fine:
from a collection of ME1 quotes:
Saren Arterius: Is submission not preferable to extinction?
Oh Bioware, I love you so much.