SubAstris wrote...
As it has mechanisms to allow Shepard's survival, then yes.
I doubt any of those mechanims in the unused back area where no organic has been before (according to mister Catalyst).
Also it can be boiled down really fast. The area Shepard is standing in is open to Space aka there must be Mass Effect Fields keeping the air inside the area. However Mass Effect Fields are gonna do absolutely nothing to the heat wave hitting Shepard and considering the size of the explosion and Shepards proximity (litterally within the blast radius) then taking into account the state of Shepards armor we are going to end up with the suprising conclusion of Shepard beeing utterly vapoized.
Off course that is after he survives a wave of energy with force enough to push around Reapers and debris in the space around it and a smaller explosion directly to the face before that. If he somehow survives that he also has to have been so extremely lucky as to the Mass Effect Fields beeing intact so he is not exposed to vacuum...