This has actually already happened, but with the 'synthetics and organics cannot coexist!' claptrap.
The first and only pre EC playthrough I did, I didn't have From Ashes downloaded. Playing through now, with an ending that, while still total bollocks, I can at least live with, I decided Javik was worth it for the extra squadmate, dialogue, and added comedy.
I learnt two things about Javik through this new playthrough:
Firstly, he's such a massive toss pot that he's actually endearing.
And secondly, that he will not shut up about how evil synthetics are.
Without From Ashes, the entirety of ME3 goes out of its way to show you that man and machine can live together in peace, and that we are more alike than different.
Javik however gives nothing but absolutes on the subject, synthetics are fundamentally different, wrong and dangerous. And what's worse, there is no dialogue to disagree with him about it. At best you can give some half hearted, naive sounding optimism that he's wrong, but you never get to point out to him that they're riding around in living proof that it's total claptrap. Never mind the fact that he claims that all organics are more similar to one another than any synthetic, despite every interaction with EDI or the Geth saying the opposite, and Javik himself being pleased that no one in this cycle understands him.
Similarly, you can't properly defend legion against him, no matter how friendly Shepard is with Legion or EDI, Javiks total contempt and threats of murdering them go completely unchallenged no matter what you do. In an argument between Javik and EDI, siding with EDI doesn't actually defend her or support her point of view, it merely tells them both to stop fighting.
From Ashes really rams the anti synthetic agenda down our throats frankly, without ever baking it up with any proof, and deliberately avoiding or ignoring everything that disproves or even challenges that idea.
I do however find it ironic that Javik, the only character other than Space Hitler to even raise the idea of coexistence being impossible without Synthesis, is the one character that would 100% pick Destroy every single time.