Rifneno wrote...
I stopped reading at "Catalyst is genuine and trying to help Shepard".

"The relationship is symbiotic, organic and machine intertwined, a union of flesh and steel, the strengths of both, the weaknesses of neither! I am a vision of the future Shepard, the evolution of all organic life!" - Saren "Marauder Beta" Arterius
But yeah, synthesis sounds awesome and totally scientifically plausible!
No, synthesis still sucks.
But consider the fully indoctrinated. They're either totally mad, or they lost ALL hope (Saren, Benezia, Kenson), allowing the Reapers a stronger foothold in their mind.
If TIM in the ending isn't real (and is just a manifestation, like Anderson), then the real TIM may only look haggard, but not huskified (I think there is ONE shot in the game of him in-person, and he looks more tired than his holograms but still organic). He may also still have a 'legit' (kinda) plan to stop the Reapers.
And he wouldn't have fallen why? Because he still has hope. The problem is just that it is a weak hope, and only for humanity, not for anyone else. Renegade Shepard may be under the same lines - he has hope, but only for a more select few of the galaxy, especially if one is a human-centric renegade. Paragon Shepard does still get the benefit here, because he has hope usually for at least almost all of the galaxy.
This could mean that Synthesis is a victory by the Reapers (in ME3, but who knows what a possible ME4 might bring), Control is a stalemate, and Destroy is a defeat by the Reapers. Refuse is also a victory by the Reapers but they are angered that Shepard never resisted. He is useless to them now.
So if all three endings can be transferred to a future game (hypothetically), one could choose Destroy for a straight-forward hero victory like Destory-ME2 and SaveCouncil-ME1 were, but Control for a more complex story, and Synthesis for a more heartwrenching one. All may bring victory over the Reapers with the right setup (character relationships, EMS, assets, previous choices), or defeat under them.
A small example of this is the Citadel Coup. You always stop it, but sometimes VS dies, and sometimes by your hands, or sometimes by a squadmate's hands, or sometimes the VS stops Udina, or sometimes you stop Udina.
Imagine the same scenario, except with you indoctrinated and your team, depending on choices, being able to kill you, stop you, or even persuade you to resist?