What I find always breaks my game is when NPC's don't interact with your progress in the game; specifically when the game allows you to be royal, feared, loved, praised, hated, famous or laughable. Will the NPC's interact with the proper respect with whatever stage you are at in the game without repeating the same arrow in the knee lines?
BioWareDAI The NPC's in the world will react to what state you've put the world in. Though some NPC's consider themselves important enough to ignore that or they just don't care who you are because that's the sort of person they are. - Cameron Lee