Yeah, Andrea is the worse. I'm hoping she gets killed off. The writers really gave her the hammer after the first season. She just slowly became the most hated character on the show. It's a pity because I love the actress; she was great on the Mist, but wow, she pisses me off so much in this show.
Anyways, a lot of speculation about the Dixon brothers dying has been made on the IMDb boards. I'm not entirely sure, but my guess would be these people die: the Dixon brothers, Milton, the Governor, Judith, Carol, Beth, Hershel, Tyreese, Andrea, and Martinez. Carol or Beth might take the place of Lori from the comics (don't want to give spoilers to the comics so I'll just leave it for people who know).
Love this season so far; although, the first half was definitely better than the second. Regardless, my favorite episode of the entire show has to be either "Seed" or "Clear" they were both awesome.