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[TJByrum]

When I play Mass Effect games I have one thing in mind: be a Paragon.  So when it comes to choices or whatever I ALWAYS choose the Paragon option.

However there is one exception:  the Genophage.

It would appear as if anything concerning the cure for the genophage is deemed 'Renegade'.  And yes, I always try to undermine any attempts to cure the genophage, whether that includes sabotaging stuff or killing people.

The genophage, like war, is a necessary evil.  If not for the genophage the entire galaxy would have no doubt fallen under Krogan control.  The Citadel Council would have been defeated and many of the other more-becoming races would either be wiped out or reduced to nothingness.

Sure, you're not suppose to genetically restrict an entire race like the salarians and turians ended up doing, but it is for the better of the galaxy.  Because of the genophage, the Krogan are kept in check, which is a huge priority - no one wants another Krogan Rebellion.  Of course if I was engineering the genophage I would have at least made it 1 birth every 500 or 1 birth every 250, or something to reset the Krogan's to their pre-salarian-interference statehood.

I never understood why Shepard is so intent on 'saving the galaxy' when curing the genophage is his idea of a paragon.  Curing the genophage, as indicated by Wreav's dialogue, will only start another Krogan Rebellion, and upon doing so will kill millions, if not trillions of other individuals, including humans, turians, asari, salarians, and other Citadel races (I don't feel the Krogan would bother batarians and the like.