Ninja'd me, I was just about to say that 30 Days of Night are some of the most brutal vampires I've seen in films for a while. Both their design and how they're portrayed are heavily influenced by sharks, which is what a vampire should be. Not sexy, not misunderstood, but vicious predators fuelled by wanton blood-lust and destruction.
I agree that the 30 Days of Night vampires are a definite breath of fresh air after all the "sparkly" vampires; the first film was (as is the case with most movies) better then the sequel (IMO).
Vampires as monsters are a route that I would like to see played out, should Dragon Age ever get around to portraying them in the setting. However, I would rather see an intelligent and cunning vampire as opposed to a mindless monster for us to stab. A vicious predator yes; but one that is capable of 'acting' human; a vampire that has set themselves up as a lord or a politician in human society ≠ Twilight, 'sexy' Vampire.
The Venture Clan in the World of Darkness RPG, for example are intertwined in human society; acting as businessmen, or politicians; and while they can use sexuality to get what they want, I would not group them into the 'sexy' vampires that are running rampant throughout fiction. They can easily rip a man's throat out, but they are smart enough to realize that killing any human in sight is only going to unite the mortals against them. A vampire that has positioned themselves so that their food will do the work for them, is far more dangerous then a monster running around the countryside eating the occasional peasant.
A Vampire that is capable of blending into human society; even if just as an act; is also capable of being reasoned with, and I personally would like to interact with the various non-human(elf/dwarf/qunari) creatures of the setting on more levels then "Evil Monster. Stab." Maybe allow players to bargain with the Vampire; we know that they are far more powerful then normal humans, and could quite possibly give us a huge advantage over our enemies; but the downside is that we are allowing a monster to remain free. More "Deals with the Devil" scenarios need to happen in this setting IMO. Would a ruthless Inquisitor allow a monster that eats babies to remain alive, if it meant that you would gain an ally more powerful then all the soldiers you would have got by riding the town of the menace?