It would be nice to get the official word regarding this. I fully expect that the downloadable versions being sold via the Origin store will require Origin. I'm more interested in the retail versions since my ISP's monthly cap is just 12GB/month (satellite sucks) and downloadable games are much larger than that.
The ongoing issue of EA's hostile DRM policies is one the main things that keeps me distrustful and grumpy towards EA.
Personally, I really do hope that the retail version does not require a mandatory origin client despite EA's recent track record. It would be great for them to surprise and delight in ALL aspects of the game.
If it's mandatory like ME3 was, then I'll have to see if they've modified the EULA since the last time I checked or not. I didn't buy ME3 new because of issues with their EULA/Client, and it may well be that I'll buy secondhand for console for DAI as well. Which would be a shame since it is looking somewhat better than DA2 and I would prefer to be able to reward Bioware by purchasing new if they'll just sell me a game without reserving the right to use their client as spyware, or to revoke my right to play what I have paid for in the future.