Goddamned bears tracking me! Eventually I give up and kill them, no matter how guilty I feel about it.
It's the damnedest thing! Most times if I disengage enemies will drop off after a bit. Bears are the worst for not doing so however and will track you for miles! This time around I was trying to get to the Knight's Tomb to do that quest. Giant spots me. I run, disengage, no mood for a fight. He keeps coming. I go down a big slope and he tosses a boulder after me! Finally I got to the Tomb and no way he'll follow me in there right? No, he literally ducks down under an arch to get to me. Ok big boy you want a fight well now you got it! I went into tac mode for this one so I could make sure he was hit with the kitchen sink! Took him down in 2 minutes! It's hilarious though and much more difficult than Skyrim where if I wanted to I could run out of any fight I didn't want to have!
The only guilt I have had so far was killing the Dragon in the Hinterlands. I felt bad about that one afterwards.