I remember playing DA2 for the first time, getting up to the point where I met Merrill, and literally cursing and shouting NO out loud, because I knew immediately that I was not going to be able to romance her. The nervous voice, the big, shimmering eyes that looked like they were full of tears, and the dialogue all added up to the opposite of romantically attractive to me.
I did get to appreciate her character, over time, and I wouldn't hate others who enjoy her romance, I just have very defined tastes in my old age, and as a fictional character, Merrill wasn't my cup of tea.
I liked Isabela from the beginning, but I wasn't really into her romance until the second or third playthrough. She even left me on the first playthrough because I was too busy worrying about Anders and Fenris's rivalry/friendship points in the first act.
I plan to spend more time with Sera and the other female characters from the beginning this time, even though I'm still a little annoyed at the ratio of companions. In DA2 it sucked feeling like I really *wanted* to appreciate the female characters more, but because the guys in the game are "louder" in their needs, they got more attention.