Almost every example of AI came with conflict that was not just expected, but disastrous or potentially disastrous. There has been *0* where an AI emerged without conflict and danger, at the very least.
-Citadel AI sees that it is illegal, and freaks, forces us to kill it or it kills itself
-Luna VI was made as a weaponized military training tool, and freaks (remember that this is technically EDI's origin; the other part being of Sovereign's code, a robot that we *destroyed*)
-Geth wanted to be more than tools, and the Quarians freaked
-Overlord was a different sort (a merging of AI and 'NI'), but regardless, it freaked out even more
-Javik's story, if we are to believe it
It is a thing. Only exception I can think of is that Cerberus News story of the one ship.
But like I was saying - it's BESIDE the point. Amazingly, the Catalyst might at least be right that the Leviathan is part of the problem
. WTF?
Because conflict, control, domination, war itself is not inherent to any specific type of life. We all do it. The Leviathans, probably like the Prothians do, see conflict between organics to be 'natural evolution'. The Levis won out with that. Woo, apex. But then there's all these organics being wiped out by synthetic beings they they create. Boo! Why? Because organics believe that conflict and control are specifically of their domain.
And its THIS stuff that is core to everything we see in the trilogy. Entities in conflict, entities destroying, entities wanting to fight those different from themselves.
The Catalyst is a lore dump. We just don't have to agree with its conclusions. It's the friggin Reaper God.
I think a problem is that we're experiencing the stage of the Reaper experiment like when Mordin was experiencing the stage of the Krogan situation when they started to naturally adapt outside the genophage's confines and attempt a resurgence.
We don't see the past cycles. We don't see the original Reaper cycle. We don't see the devastation that synthetics may have wroght onto organics in the past.
Basically, we lack context. And that, in itself, might be okay. Shepard is a character that constantly lacks context. That's what happens with your core archetype is a soldier that mostly sticks to his mission.
But don't mistake 'Oh I was able to make peace this one time temporarily between an organic and synthetic species so we could fight this other biosynthetic species' to mean 'nah we all good with synthetics now and problem solved'.
~~~
Honestly, this reminds me of Dragon Age - just obviously on the much more huge scale. During DA:O and kinda DA2, it's VERY easy to sympathize with the mages overall, in the larger scale. Oh, they had that giant corrupt empire? Whatever, they deserve their freedom (this is actually still my position btw). Oh, one screwed up mage could quickly kill a whole town? Whatever, the Circle system is busted and Annulment is immoral.
Well, get ready now for a story where the Fade is torn open, Mages are largely 'apostate', and we see what happens with more maximum freedom for them. And it'll involve a lot of deaths and demons.
Get ready for the same in Mass Effect. Really, get ready. I know the slides show some nice stuff, but get ready for organics to RUN WILD with messing with synthetic life. The foreshadowing is all over the place.
Synthetics are stand-ins for order. Organics are stand-ins for chaos. (at least on the galactic scale) This WAS here since ME1, no matter the protests otherwise. We can use our experiences with other 'order and chaos' toned dilemmas in order to decide what kind of person we are. Do we 'shut down' the Krogan, or do we try to temper them, or do we outright embrace the prospect of peace with them? No, it's not the same as synthetic vs organic - but it doesn't have to be. It's just one major theme which assists larger ones; ones like choice, intelligence, chaos, and order.
Hint:

The rest is up to you.