I said that Tali and Garrus were incestuous and that I believe Fenris hooks up with Isabela because he's one of four women he knows. You replied that he seemed to care about her and they were friends with benefits.
I expect Fenris cares about Isabela and Tali cares about Garrus, but that has nothing to do with that I dislike about these pairings.
Sorry about that then. I was only talking about Fenris and Isabela rather than responding to your entire argument. My mistake: I'll respond to your enitre argument now
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If I'm correct, your reason for thinking that Tali+Garrus is incestuous is the idea that Tali has adopted the Normandy as her family. While I understand, I think it's projecting human ideas on the the idea of "family" that has less to do with how Tali meant the word. I find it very unlikely that everyone on a Quarian ship is closely genetically related to each other, and I find it equally unlikely that Quarian pairings never occur within the populous of their own ship.
While I admit I've never played either Tali or Garrus' romance (I don't really see a reason to play straight characters...) I feel like Tali+Garrus makes way more sense than either of them+Shepard with that whole different amino acids things. (It's ridiculous by the way, while it is true that we can't extract any nutrition from right-handed sugars or amino acids, they almost probably wouldn't kill us. Example - Right handed Carvone smells like Spearmint, left handed it smells like Carraway, both are harmless. I've also seen some people suggesting we should use right-handed sugar as sweetener because it still tastes sweet, but we're incapable of digesting it.)
Sorry tangent, anyways, Tali and Garrus would have probably regularly shared meals, since they're the only people on the ship with right handed chirality. I guess it was easy to miss, but they flirted over intercom for pretty much the whole course of the third game. It's not a perfect romance, there's an element of desperation to it. I doubt they would have hooked up if the end of the world wasn't happening. But it was happening, and I think their romance makes sense in that context.
Sorry that I'm longwinded, but I'll be shorter for Fenris and Isabela. My issue with your argument "She's the only woman he knows" is that it sort of implies to me that Fenris would have sought out sex regardless and that Isabela just happened to be the best candidate, which I just don't think fits in with his character. You could argue that the literary decision to pair Isabela and Fenris was just a result of the fact that they were the only compatible people in the group (though I will still head-cannon that GW Carver and Merrill eloped after the whole Meredith fiasco) and was largely a poor writing decision, and I wouldn't have anything to argue. I'd disagree, but you're certainly entitled to your opinion.