Yeah, going with "new galaxy" and "sequel". Maybe some lore issues for choice sticklers, otherwise a way to circumnavigate ending choices and give fans a new template to work with.
I'm happy to explore wherever, but as I've said elsewhere I find the "ark(or whateer) sent to new galaxy detached from the milky way" concept to be tremendously less appealing, interesting, and consequential to "canonised ending, direct sequel in milky way". I find the idea of meeting new, space faring races in our own galaxy that remained out of contact from citadel space during the Reaper War to have far more interesting implications and potential than simply meeting new faces in another world detached from our own.
But whatever, I'm still going to enjoy the **** out of it.