I am not saying that. It can be done, but it is not always good and can be executed poorly. I watched Pacific Rim and really enjoyed it, but there is more chance of it not working or becoming obvious the more heavily it is relied upon in a film or a series. That's what I'm worried about.
Read both of my posts again -- I'm arguing the execution itself stands attest to quality. But that's not something that is exclusive to cinema. Ultimately, it's also about whether there's any larger interest to make it. The idea itself needs a solid pitching to even be accepted for production, then there are bunch of the other procedures it has to go through. Most video game adaptations never go beyond the production line before being canned. Speaking from experience here. This is partly due to loss of interest, like people leaving the project, or busy schedules with other film.
From the way I see it -- Animated Series can potentially be just as bad as that of live-action. if, we are talking about Mass Effect, then I'd argue the artstyle doesn't sit right with animation, at least not comics.
Right now, Duncan Jones is working on a flick based on WoW, so it's interesting to see if he can pull that off. He's a director I like, despite only having made 2 films so far. One to watch.
I'm not saying your worry is misplaced -- I am saying that it's a double edged sword and it counts for both animation or live-action alike. There are several factors that need to be fulfilled.