I can't wait to see how they make the head of a large and powerful organization like the Inquisition disappear.
"Until one day Inquisitor Lavellan did not return from her journeys. Some say that she was finally caught by the Venatori, others claim that the Abyssal Dragon rose again to seek vengeance, or that she stepped into a rift to claim her seat at Andraste's side, and the most improbable tale yet is that a wolf took her."
But seriously, I think they'll either have to kill the Inquisitor or else let us play them again Shepard-style and I don't see that happening. Quizzy is too powerful and the Inquisition is too powerful. I can't see how it could go away without creating a power vacuum and I can't see how we could play another char when the quizzy is off doing awesome things without us. It would rankle and it would require the writers to make decisions for the quizzy that might not fit with her char. So yeah ... death?
Or you know there's always the wolf. I'll take that option, please.