Well, it depends. I know better than to pin my hopes on anyone, but I'm one of those candle-bearers for a Varric romance. I don't expect it, but I do have a sliver of hope. I won't be disappointed if he isn't, since he's my DA "best bud" and I'm just thrilled to have him around.
Sera is great, but so far isn't really my type. She's feels to me more like a kid sister, someone that's going to be bratty and possibly quite immature. Those aren't marks against the character; if anything, I adore her for those reasons. She just isn't my taste to romance. While I'm still quite happy for the Cullen fans (sincerely,) he's never done anything to make me want him as a LI.
Otherwise, I don't know. I'll really have to wait and see who's available. Even then, I'm going to be careful about setting my expectations in stone.
The first time I played Origins, I thought I would love Zevran and find Alistair completely boring, not my type (I'm not into short blonde hair/blue eyed men) and too naive. Turns out that Zevran isn't my favorite LI, and Alistair has turned into my favorite LI as well as my second favorite friendship in Origins (my first being Morrigan as a lady Warden.)
Time and time again, BioWare has taken my expectations and turned them on its head. I wouldn't put it past them to surprise me yet again in Inquisition. 
I'm hopeful in regards to Varic becoming a romance interest, if only because they let you learn a little bit about Bianca in the comics, and also because he doesn't seem to be the narrator this time around. Basically they revealed that there IS a romance related story that Hawke never learned... That said I'm fairly certain of all the potential romance characters, he's the one that I'd expect to be exclusive to certain races.
I'm honestly looking forward to the possibility of Iron Bull the most. The more I learn about his character the more excited I get. He's a lot more amusing than I thought he'd be when I first saw his concept art. If I don't get to romance him, I'll probably be a bit disappointed...
At least I know Cullen's an option though, I've been hoping for something with him since I learned he didn't actually go on a murderous rampage through the Circle like in his DA:O epilogue xDD