Even as a crazy crazy theorist that believes that we may be playing some sort of NeoShepard...
I don't want Joker to pilot the next ship. Or rather, I want it to be as optional as Ken and Gabby in ME3.
New ship too. Even if it might might might incorporate parts of the Normandy.
Even EDI aspects should be optional, at least mostly.
I know I probably don't make sense with this post. Basically - I want every connection to the Normandy SR-2 to be optional but still a choice, while the default path for new players joining the series in 2015+, is much more unrelated to the Normandy SR-2. Even while I'd probably cling to most aspects of the SR-2 that I can. Yes, join my ship Joker. Yes, EDI take control. Yes, fit in Normandy parts. It'll all make a better ship just like previous-game stuff made for a mostly better ME3.
Of course the more of the old that I cling to, the more of the new I should be forsaking in return. Maybe other ship parts are technically more advanced in many ways. Maybe not having Joker gets me a replacement that is better in some ways. Maybe not having EDI gets me an entirely different AI that is better and worse in its own special ways.
Think ME3 character/story replacements on overdrive. Aw yeah.