In short, girls, in BioWare games: do NOT straight-romance humans unless you're prepared for the inevitable fan tears. 
I have a sneaking suspicion that we straight girls are gonna get screwed either way... (erm, pun not intended....) Cullen is going to go crazy from lyrium addiction, and Iron Bull is going to leave us because, the Qun. If LIs, Solas will betray us by being in cahoots with the BIg Bad or decide he likes being a lonely hermit just fine, thanks, and Blackwall will leave us for his Calling. And Varric will decide he'd rather pine over his Bianca than be with us - or he'll stay with us but refuse to stop using "Bianca you minx!" as his battle cry.
If you'll all excuse me, I'm going to make myself a strong drink now 
Edit: Eek! I just came back an re-read my post and, just to clarify, it was supposed to be a joke - albeit a rather twisted one. My hope is that the romances are designed in a way where they could end well or tragically, depending on your choices in the game and how you approached the relationship. And I hope that any tragic endings get evenly distributed among genders because this particular trope is one that, as a straight female, is starting to seriously peeve me off.