I used to crash from this all the time, but only during cutscenes. I messed with some of the in-game graphics settings a couple weeks or so ago and somehow that has fixed it. I haven't crashed a single time since, and I've done a ton of cutscenes. I also know that's what fixed it since I somehow managed to reset all my options back to the default on accident and I immediately started crashing again until I set them back the way I had them. I know this is just another anecdotal fix and probably won't work for everyone but I'll post my settings here in case you want to try it. My graphics card is a GeForce GTX 660 and I keep the drivers up to date. I've done nothing else other than alter in-game settings, I've never done the underclocking thing or altered anything outside of the game. Anyways, here's the graphics settings:
Specifically I suggest messing with the post-process quality, post-process AA, and multisample AA. Again I don't know if this will work for anyone else, maybe it's just some weird concoction that works for my computer, but it definitely did solve my problem.