It's a great game and shows Bioware are returning to form but here are the non M+KB Issues on the PC I've noticed
Gamepad Controls
1. Unused D-Pad buttons (would be useful for things like quickheal for example)
UI
1. Inventory real-estate:
-Huge font size meaning a lot of time needlessly scrolling through lots of items. (understandable on consoles since you're generally sat further away but not on PC)
Character Creator
1. The lack of a Black Emporium/Mirror of transformation.
2. The omission of DA2 hairstyles and tattoos
Tac Cam
1. Resets to character after swapping to a different character
2. Doesn't zoom out far enough (understandable in interiors since the assets probably weren't built like DAO and older Bioware games were but not in the great outdoors)
3. No place to stash any loot you want to keep but don't want with you (at least so far - no storage in Skyhold that I've found)
AI:
1. Party members getting stuck in caves
2. Party members continually jostling about
Looting
1. Small radius leads to jumping instead of looting. Very annoying in such a long game
2. Landmarks and things like ladders sharing the same ping sound as loot - another annoyance
GFX/Performance
1. Crossfire smoke fx pure white
2. Crossfire terrain flicker
3. Mantle random framedrops/hitching during gameplay
Other (preference):
1. Skyhold Grandma clothes... (nuff said)
2. No individualised 'Hide Helmet' option (I'd rather Cole kept his hat on - not a Tom Jones reference)