I've been doing a little digging and so far, patch3 (on PC) broke:
1. Codices. A codex will give me experience but will no longer give me a text window. It does unlock a brand new codex as per normal, which I can then search for my codex for (what a pain).
2. MSAA. Toggling this on, now, causes an instant crash as soon as I try and load or start a new game. Subsequently opening the game crashes on start up and I have to manually edit the profilesave_profile to default values to access the game again. No way of doing it with the game. This may or may not be related to nVidia's 345.27 drivers.
3. Walk/Run toggle does not appear for me. I have no command line arguments, no mods, pure vanilla game. Doesn't show up.
Will add more later, it's been a long day and I've forgotten some.,