I didn't listen to the podcast, but IIRC the two options they had in mind for resolving that whole thing were a) destroy the Reapers and hope and pray that everything will work out (in typical paragon fashion), and b ) allow humanity to by Reap'd because the existence of a Human Reaper would somehow fix the problem, which doesn't make sense, but then it was just a vague outline of the idea.
It definitely needed fleshing out, but the idea of Mass Effect technology being used to regulate dark energy in the galaxy is an interesting starting point imo. The problem with it is that it kind of doesn't allow for a galaxy without Reapers managing everything, unless organics somehow come up with a solution that hyper-advanced machines couldn't in a billion years, which is kind of silly.
Honestly the Organic/Synthetic thing isn't a terrible idea either, I mean I remember seeing theories that the Reapers were preventing a technological apocalypse being posted around the boards as early as pre-ME2. The problem with the current ending was the execution. If the whole SynthOrg thing had been properly delved into over the series it would have been better, instead we got some poorly delivered exposition by a character that ruined what were supposed to be the antagonists we'd spent 2 1/2 games worrying about. I guess I'm saying DE isn't inherently better or worse than the SynthOrg reveal, it's a matter of how it was handled.