Oh for the love of Bhaal.
Just because you have gotten used to something doesn't mean that mechanic isn't inherently flawed. Let's take needing to hold the mouse button to move as an example. To use the universally-loathed metaphor of cars: imagine that you have to use both feet whenever you want to brake or accelerate. Is it possible to drive using both feet at the same time to brake or accelerate? Yes, of course. But should it be necessary? Is it inefficient and indicative of poor design? Will driving like that for extended periods tire you out more than is necessary? Absolutely.
It is because so many of you are so complacent with mediocrity and poor design that developers keep giving us exactly that. Bioware has clearly designed this game for consoles and is giving you, the PC gamer, the middle finger. Despite that, you just smile and go merrily on your way. It would be like going to a Starbucks and watching the barrista spit into your cup, then taking it and gulping down with a smile on your face. Open your eyes and get a clue. People like me are tired of giving them to you.

Pretty sure you can move with WASD keys, which should be natural for any PC master race gamer. What are you going on about?
Your analogy is disgusting as it is irrelevant.
A bartender spitting in my drink implies that there was intentional sabotage in the product as a result of malice towards me. Victimizing yourself much? This clearly isn't the case. If there any flaws in the game, they are a result of time and budget constraints. Nothing more. Nobody is spitting in your drink. Ugh...
You sound like the type of person that goes on dating websites. movies, or restaurants and picks apart every flaw in every prospect, rather than accept that nobody and nothing is going to be perfect.
Hey. That's fine. It really is. I couldn't care less how you spend your time and energy.
Just don't think that you're better than those who choose to get over minor speedbumps, move on with their life, and be happier for it.
Pretty sure the DAI controls are natural to me at the moment and I don't feel "tired out" by fixing them any more than I was "tired out" by downloading a thousand mods to fix Skyrim or remapping thirty controls on WoW. Any lingering issues I have with control usage will hopefully be resolved in the near future. In the mean time I'll have fun enjoying the game rather than complain about it.
Buck up and stuff that clue up your wit's end.