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[Cure Optimism]

I'm at the part where you find the female Krogan who is supposedly cured of the genophage. And I remember saving Maelon's data in Mass Effect 2. I guess some of the females survived his experiments and were taken to the STG base. I thought that Maelon's data was incomplete, and therefore not an actual cure for the genophage. How could Eve be cured if she was experimented on with incomplete information? Was it just happenstance that she was cured and he never knew? Also, Mordin describes it as if it was just a natural mutation rather than an effect of Maelon's experiments.

[Vazgen]

Maelon's experiments were brutal. The surviving females were brought to Sur'Kesh where Mordin tried to stabilize their condition, but complications from Maelon's research claimed the lives of all females except Eve. 

IMO it was a combination of Maelon's research, natural mutation and Mordin's help.

[Cure Optimism]

I'm trying to get this straight because I thought all of Maelon's tests were fruitless. Now it seems that they were essentially a cure, but the fatality rate of those who were given it was extremely high. Maelon's data contained all the information of the experiments he has done, and the results. Eve was just lucky and managed to survive, was taken to Sur'Kesh for further studies. Mordin was working there, leaked information about the sickly and cured females to Wrex to start political upheaval to get them released. On the Normandy, Mordin combines his own scientific knowledge and Maelon's data to stabilize Eve's condition, and uses her tissue sample to create another genophage cure that won't make the recipients sick.

 

But that makes me think, if Mordin has Maelon's data and it contains all the experiments he has done, all he has to do is replicate it on some other female Krogan and get the same results. In fact, it makes me think that Maelon's data actually has nothing to do with the genophage, and Mordin only uses it to stabilize Eve's condition. Mordin just creates the cure out of Eve's tissue.

[Vazgen]

The experiments Maelon's done were barbaric and Mordin would never repeat them. He says this about the data:

ME2: "Maelon's work could cure genophage. Don't know. Effects on krogan. Effects on galaxy. Too many variables. Too many variables!"

Meeting him in ME3: "Indeed. Data Saved but not complete. Lacks crucial details to reconstruct cure but still useful for synthesizing from living tissue."

Med bay dialogue: "Maelon's data thorough. Fortunately detailed as well. Have used notes to improve her condition."

Regarding Eve's immunity: "Genophage targeted hormone production during pregnancy. Modification project used same modality. Her 'immunity' totally different. Targeted glands now obsolete, like human appendix. Other glands mutated to produce proper hormones, enable viable birth. Also explains her weakness. Gland substitution imperfect. Health trouble."

The research is helpful for synthesizing the cure from Eve's tissue without killing her. The cure itself is due to the natural mutation that was a result of Eve adapting to Maelon's experiments.

[cap and gown]

 

The research is helpful for synthesizing the cure from Eve's tissue without killing her. The cure itself is due to the natural mutation that was a result of Eve adapting to Maelon's experiments.

 

That is not how I interpreted that at all. My interpretation is that Maelon was trying to alter gland functions so that alternate glands could produce the hormone(s) needed for successful reproduction. That way it avoided trying to fix the glands targeted by the geonphage. The problem was that Maelon hadn't gotten his cure just right and that some of his alterations also weakened the immune system.

 

The cure was due to Maelon's work, but his work was incomplete because it hadn't solved the problem of weakened immune systems. Kind of like how chemotherapy kills the patient, it just kills the cancer cells faster. How much better if it only killed the cancer cells?

[Excella Gionne]

You use what you can get. Mordin was able to work upon Marlon's data, and although he disagrees with Marlon's experiments whole-heartedley, it was not a waste of data.

[Vazgen]

I agree with you, that was the aim of Maelon's research.

"Position of tumors indicate deliberate mutation of adrenal, pineal glands."

"Conceptually sound though. Genophage alters hormone levels. Could repair damage with hormonal counterattack."

"Genetic sequences. Hormone mutagens still steady. Protein chains, live chains, cloned tissue. Very thorough."

 

What Mordin did to create the cure.

"Need to synthesize base antigen from female. Also requires healthy male krogan tissue. Will need a sample."

"Will need to counteract shutdown of redundant nervous system, adjust neurotransmitter levels..."

 

Impact of Maelon's data

"Procedure traumatic for Eve, but not lethal. Maelon's research invaluable." Eve survives

"Stress sampling too intense. Too much trauma." Eve dies

 

Now, I have no idea what stress sampling is in medical terms but I assume it has something to do with "synthesizing the base antigen". 

[sH0tgUn jUliA]

Love the OP's forum name. You are ready.

[cap and gown]

 

Now, I have no idea what stress sampling is in medical terms but I assume it has something to do with "synthesizing the base antigen". 

 

Heh, most of what Mordin says is just bio-techno babble.

[Cure Optimism]

If anyone is still looking at this, I have another question. I don't want to make a ton of topics for every question so I'll put it here.

 

Who has the final say in what a particular government does? Shepard attempts to appeal to the Council for aid in taking back Earth, and yet people make it out like the Councilors for each species don't really matter. You end up dealing with Turian Primarch, and the Salarian Dalatrass. If all you need is their support and in the end whether they want to help or not is up to them, the Council really doesn't matter. What role do they play?

 

Who in the end decides what will happen? Shepard says that he'll bypass the Council and appeal directly to their leadership, and I was under the impression that the Councilors themselves were the leaders and decided what to do.

[Alamar2078]

I believe the council is similar to a United Nations in that they can make policy pronouncements and make it easier to coordinate / negotiate between species but the individual councilors are still just ambassadors that may report to someone else in their own government.

 

Also note the United Nations doesn't exactly have an army of it's own.  Any army it has comes from each member's forces that volunteer to act on behalf of the United Nations.