Daveliam already said it better than I could but yeah. There are tangible differences between men and women, biologically. Arguably this can make them better suited for certain tasks. Gender however is a set of beliefs, expectations and behaviours TIED to sex but rarely do they make any sense because gender is also tied up in things like religion and tradition. It's messy and nonsensical. And the world would not be worse of if these attributions based off sex were swapped around or changed or a higher emphasis was put on something different, it would just change. And they do, regularly. And anything that is so mutable and changeable and without real benefit or detriment does not mean anything, they do not need to be followed, they do not need to respected, they can ignored or conformed to because at the end of the day they mean very little tangibly. Although societally they mean quite a bit. But that's a different thing.
Let me put it this way, because I do believe there is a common ground of understanding for us in this thread at the very least.
I don't agree necessarily on the tangible angle, BUT I do agree that in our society, it's not that important and yes it is very much a huge social issue.
It seems that we here can agree and we know that biological sex is how we define gender scientifically, but in society, like race and so on, it is less rigid, and it is something that people know is a socially tied thing.
In other words, not everyone is claiming that people are men or women factually because they are trans and want to be, but because it is simply respectful to do so. I would be fully on board with that if more people treated it this way, rather than trying to force it down as a fact in all aspects period. Not saying Bioware is doing this, and unfortunately I think people from both sides of this are bringing in extra feelings outside of this conversation here, which is why I never even expected Daveliam to say what he said about Biological sex. Color me surprised, not many people would actually say that.
Anyway like I said, this is indeed a social issue, and I don't have the need to call someone out of what they want to be called, which is why I stick to calling Krem Krem. It's easier since where I'm from, referring to Krem as he is very alien, and I'd slip up even more trying that anyway, if I was inclined to do so in the first place.
I admit, the whole practice is not something I sign on to at all, and I'd prefer people stick to biological definitions, but they don't and I'm not that uptight to care enough to tell everyone about it every chance I get. Hence why to me, Krem is just Krem.
edit: Well, I might've spoken too soon on bioware, as I mentioned with Sten who seems to go against what's said in DA I, but whatever.