It's a very clever idea and advance in trying to create an emerging narrative. It's not necessarily as rewarding or as great as people make it out to be but absolutely worth it.
It's a good place to start for future games. Let's put this in a Bioware game and mod it appropriately. Set-up, you are from Tevinter, and have been framed for a crime you didn't commit. People want you dead and you have to navigate the byzantine politics of the Tevinter Underworld and it's high courts to prove your innocence. You have Four magisters an three crime lords that are hostile to you at the beginning of the game. These are set characters with back story and personality whose views on you change as you make decisions. UNDER them are their right hands and three - four Lieutenants. These guys use an expanded version of the Nemesis system to decide their own motivations and the level of loyalty they have towards their superior and are randomly generated each time you play the game. The Head honcho's will send the best of their randomly generated people to do their bidding, so the overall goal may be the same each time you play...but the skills/goals of the guy running the op change each time. Perhaps you can talk one guy into being a double agent, or maybe the fact you killed another's Brother means killing you is more important than doing what his boss says.
It would be a pain to make real....but it's a good way to take the Nemesis system a step further.