You've already made this thread nkga.
Years ago, and with a different focus. Now I just want the quote's sentiment to be discussed. I think the Illusive Man makes an excellent point, and I don't know how we, as the audience, are supposed to take it. He's indoctrinated, the Paragon arguments are about how his reach is exceeding his grasp, and how that can lead to only bad things. But then the Catalyst reveals that control of the Reapers is possible, so the Illusive Man wasn't completely insane after all. So then maybe he actually did have a point all along? Great civilizations should control rather than destroy? Then is Anderson wrong? But the whole game told us that "Dead Reapers is how we win this," and "We destroy them, or they destroy us."
It's simply another piece of the frustrating ambiguity of the ending. What bothers me most is that people like to frame the Illusive Man as wrong about everything, that his entire philosophy is fundamentally broken. I don't think it is. The biggest problem is that he takes everything to an extreme. Human evolution at all costs, human dominance, etc.
What if Cerberus actually worked with the galaxy to build the Crucible and proved to everyone that the Reapers could be controlled and used for the benefit of all? From what I understand, they didn't do that in the story because they feared, perhaps rightfully so, that no one would listen to them because the majority would want the Reapers to be destroyed, and the Illusive Man was bent on specifically human dominance anyway. But I still wonder if the galaxy could have warmed up to the idea of controlling the Reapers. As it stands now, the story makes far too many players take a very strange anti-progress/technology stance that I don't think they really believe, all because the Illusive Man had to be invalidated and the giant Lovecraftian monsters had to be killed. And you can't question the mission to kill the monsters, because if you do, then "you've gotten a little too close to the enemy." Frankly, that sounds like Indoctrination.