I think it would be an alright change of pace. Wouldn't be ground breaking or anything to me but it would be different.
I wonder if it would fit with the lore though? Technically most Links are different versions right? I'm not sure if the in story lore says they're the same person or if it's just a role that has to be constantly fulfilled.
That character's role has always been portrayed by a male, either an adult, a young adult, a teenage or a young kid. Never it has been changed by gender, and the reason is that's the archetype, a young male elf, dressed in green and white, with a funny hat, a shield and a sword.
What would happen if I changed Jill Valentine into a male called Bill Valentine? You get a total different character who needs new characterization - based on his gender - and that has nothing to do with the previous, except he has a similar role in the story.
What you get for swapping sex is pleasure suited for a sick mind. I'd never change neither the gender or the role of any famous character, videogame intended or not, unless there is a specific and strong reason to do that, remaining on the same base of the main opera.