I'm fairly neutral and ambiguous about a female Link. On the one hand, I have nothing against it, it could be an interesting avenue to explore and it's not like it would hurt anyone or anything. If you don't want to play it, then don't. I'm sure there are people who would be curious/want to play a female Link.
I personally don't feel it would a great use of creative energy to make Link female (unless they did a game involving a Female Link/Zelda romance, that I fully support
) since the gender of Link really isn't a big part of the character nor is it that significant, in some ways Link is almost androgynous, I mean honestly when I play any Zelda game half the time I forget that Link is technically a dude. From that perspective, there wouldn't seem to be any major gain in making Link female. Why not create an entirely different protagonist in the same universe maybe? And that character could be female. Or simply focus on creating an entirely new and original character in an entirely new series, in my opinion there would be more creativity and sense (and fun) in doing either of those things than simply changing the gender of an already existing character in which the gender is barely more than a side-effect of Link. It could arguably be seen as artistic laziness, it really depends on the hypothetical game itself.
However, I wouldn't go so far as to say I am completely against the idea of a Female Link altogether nor would I necessarily not support it if it came to pass. I may not see the point in changing an existing characters gender when one could create an entirely new being instead, but I'm certainly not against changing the genders of characters in existing universes altogether, as I intimated above it would really depend on the entirety of the game, maybe the changed gender will genuinely bring something new and exciting about. Or it could not.
I won't give a more definitive one or the other opinion until this hypothetical game comes to pass and I actually try it, hell, for all I know I mind end up enjoying playing as a Female Link. Won't knock it 'till I try it 