No, continuing in the Milky Way despite silly Crucible space magic leaving an untenable situation is beyond ridiculous.
I would not argue about crucible and the rest of RGB,but situation is most certainly not "untenable".
Out of interest,did you save Collector's base or destroyed it? Because this crucial decision about aquiring reaper technology together with terra...,sorry,omegabytes of information about them played such a vast role in ME3. Oh,wait....
There is no need for RGB choice impact to be any different.
Want same default state -its decades after The War , people use implants and healing nanites,relays don't work and there are no reapers but nobody knows why exactly. There you go.
Minor variations that will allow for RGB:
Destroy - few dialogue lines that will show player that relays were damaged heavily, reapers "dead" all over,just not in the areas game "visits", but nobody knows why exactly - all kinds of myhts.
Control/Synthesis -few dialogue lines that will show player relays don't function,reapers just left and promissed to never come back, nobody knows why but there are some myths.
If Bioware does not have time or resources to include certain races that should or should not be there due to player decisions - something happened to those poor/lucky people during those decades since ME3.
Frankly,everything can be changed because writers are like God in their universe,they can create and they can destroy,they can change things - past present and future included. If there is a will,of course.