There does seem to be some multiplayer integration but it sounds optional in that you can let the AI do it based on stats you build up. This is from the leak and obviously all subject to change even if true. I think this part of the game sounds pretty good.
Deployed Strike Team Missions:
The Helius Cluster is 1000s of light years across, and you can’t be everywhere at once. As you develop more colonies, resource bases and settlements, you have to be able to keep them safe. Spend resources to recruit mercenaries and develop an AI controlled Strike Team that you can deploy to take on randomly generated, time-sensitive missions. Strike Team missions take many forms, including settlement defense and Remnant artifact recovery, which will take real-time to complete. Send your Strike Team out on a mission while you continue playing the main game and they will return, 20 – 30 minutes later, having gained rewards such as XP, currency and equipment based on the success of their mission. Spend money and resources to train your Strike Team and acquire better gear for them, which will increase their success rate and allow them to take on more difficult missions for greater rewards.
Active Strike Team Missions:
When you encounter a Strike Team mission in the Single-Player mode, you can leave your Strike Team at their base and decide to tackle the mission yourself with your Multiplayer roster of characters. You also have the option of tackling the mission by yourself, or recruiting up to three friends to play with you. The more friends you bring, the greater the challenge and the greater the reward. These missions will play out using the Next Mass Effect’s multiplayer Horde mode (more details on this later). These missions will include a variety of thematically appropriate objectives, like defending a Settlement against Khet attacks, or recovering a Remnant artifact off of a planet before an outlaw gang gets there first. By taking an active role in strike team missions, you can earn special Single-player rewards in addition to the usual multiplayer specific characters, weapons, weapon mods, and pieces of equipment which can be customized between missions. Additionally, players who join another person’s Strike Team mission will receive bonus in-game currency and multiplayer XP for helping others with their missions.
Multiplayer “Horde” Mode:
The next Mass Effect’s “Horde” multiplayer pits you and up to three of your friends against waves of enemy troops on various battlefields throughout the galaxy. Players fight together to survive increasingly difficult enemy attacks and accomplish objectives, like disabling a bomb near a colony base or assassinating a target. Progress through multiplayer missions to gain XP and earn new multiplayer specific weapons, characters, weapon mods, and pieces of equipment, which can be customized between matches. Multiplayer play will also earn you APEX funds (in-game currency), which can be used to purchase items and gear in the Single Player game.