The more Mass Effect Andromeda is different than Inquisition the better the game will be. Inquisition was a failure.
Sorry to say but I second this.
I will even take it a step further and say that I don't believe that DAI was as successful sales wise as EA/BW had hoped despite any PR spinning to the contrary from the marketing dept.
The fact that some of the big gaming sites gave DAI high scores is nothing more than the emperor not having any clothes imo. It doesn't change the fact that the game wasn't very good.
BW needs to steer clear of the DAI formula and build upon the formula established in ME3 and just make absolutely doubly sure that the writing is on point all the way though to the very end of the game.
The formula for success is right there for them on a silver platter but I worry that they are too blinded by the currently trendy totally open world pseudo mmo fomula that is watering down a lot of current games.