As for romance in Andromeda-
I think Mass Effect can, and should, have a civilian 'lover at port' romance. Whatever the 'Citadel' equivalent might be- the Arc, a home planet, or a life ship- have a civilian who has no glaringly conflict-of-interest subplot like every single Shepard option we had. Not a 'Commander and Subordinate' relationship. Not 'let's make a love boat with the crew.' And not a 'reporter too close to the subject.'
So here's a scenario- saw we had a civilian love interest in the diplomatic service. A sort of 'Ambassador Udina's assistant' sort of character, semi-analogous to Josephine from Inquisition. Let's say, for the purpose of this outline, he's a (flip-coin) guy, named... Nead.
Nead is a guy, above average looks and intelligence, who works in the diplomatic relations office as a liason with the military. He doesn't work for the player- his boss probably far outranks the player- but he's your support/contact/etc. when it comes to learning about new races or handling the Milky Way alliances internal race relations.
In the core plot, Nead is a supporting character who's mostly left at the Arc. Maybe he takes one or two away missions to visit another power- a significant diplomatic event the player is supposed to help guard/protect. Nead has views befitting a diplomat- not necessarily views you would expect or agree with (let's have a non-pacifist diplomat who can be assertive without being an *******, please), but one who balances 'talking' with 'fighting' with a reasoned emphasis on the 'talk first, shoot later' side of things.
If you don't romance him, Nead's just a friendly supporter within the Beuracracy. Bends a few rules, maybe commits a bit of treason to sneak you secrets that would help save the day. Your relationship could be warm (Anderson) or antagonistic (if you're the Udina), but ultimately he agrees with your goal and wants to support. Gets along reasonably well with companion characters, enough so that he'd work through them even if you the player can't stand him for whatever reason. You can visit him at the Diplomatic office, but he takes part in ship conversatiosn by holocom. He might be involved in, say, a hypothetical end-game summit that the player realizes is the Crisis Point.
But- if you maybe flirt a little flirt, get along well from the start... well, perhaps he offers to treat you back to drinks at the Citadel. One drink comes two, two becomes more, and before you know it he's more drunk than you (the player) and the player has the choice of taking him back to his apartment for the night or calling a taxi for him (non-flirt). If you do- and the player could have a scene in which the PC chooses between having consensual drunk sex or sleeping on the couch but staying the night- the one-night thing could start to become something more.
The next morning, Nead is surprised you're there, and wants to know if it's a one-time thing. PC can yes not. If the PC wants, though... well, Nead is a bit happier to see you in the mission briefings. And invites you back. And pretty soon, the companions know the PC's got a lover at port waiting for her/him to come home.
Now, Nead's romance arc, being both out of the PC's influence and a civilian, offers a rare chance for some relationship dynamics Bioware hasn't really changed yet. Like, military-civilian distinctions and discipline: the PC can't order Nead around to do something he doesn't want to do, and trying to would blow the relationship pretty quick. But, more importantly... we can get a relationship in which we have 'super-duper amazing PC' on one side, and on the other side we have someone who... isn't.
Not a 'best of the best' one-sentient army. Not a master hacker. Not a super spy. Not even an amazing diplomat: Nead might be above average, but the PC is beyond extraordinary. The deadliest SOB since Shepard. The most amazing Human in Andromedea... knocking boots with a wimpy bureacrat who can't even fire a gun. How's he supposed to feel about something serious becoming, well, something serious? Especially when the PC spends so much time away with more impressive guys and girls and companions. Especially if the PC has opportunities to sleep around and so on.
Play the power imbalance, Bioware. Play it. Not in that he's crippling insecure- but that he's dealing with the power imbalance, trying to be something other than 'the PC's love-toy', and that the player will have to acknowledge it to.
Especially if, when, 'the PC's lover' becomes the obvious target for someone trying to hurt the PC by proxy because they aren't strong enough to do so directly. Especially at, say, an end-game diplomatic summit of sorts. Could Little Weak Civilian, taken hostage, be a Real Man, or at least something other than the damsel in distress in a hostage crisis?
I'd dig it.