I don't do the Multiplayer, so my response is all Singleplayer.
To be honest, I like the Lift Grenade the Sentinel gets, because it has enormous damage output and a good radius. But I often don't think to use them, mostly I Overload-Warp-Throw, and that triple-threat combo usually does the job. Another downside is that they don't "home in", so sometimes I'm thinking "Throw" or "Warp" and how they arc around obstacles if you aim correctly, and then I end up blowing up an indestructible bench on the Citadel.
Still, the ability to make what is essentially an instant biotic detonation for free (so to speak) is a nice addition to the Sentinel's arsenal.
I see them as highly situational; they do guaranteed damage and have no cooldown, and when it's a squadmate's grenade you can spam them back-to-back by pausing, targeting enemy, and unpausing repeatedly. I also like how they can act as "Get out of Banshee's hug-stab NOW!" tactic. But there is a limited number, so if I'm in a situation where I have to hyper-spam grenades, it's usually because I've done something wrong.
Also, Nova, YOU ARE THE GRENADE. I find I have a much easier time using that, because when I'm using Nova it's usually because I just punched the enemy with my face using Charge, therefore it's almost impossible to miss.
If there's a grenade I don't care for, it's Cluster Grenades. I don't hate them, but I don't feel that it adds anything to the Adept. It's already such a specialized class, and any situation that would benefit from Cluster Grenades is a situation that your other powers would already be able to handle.
If Liara had them, however, I would probably like them a lot more.
Long story short, I prefer grenades for my squadmates, because they never miss, and I don't have to "think" about it so much.





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