Not even unintentional collateral- one of the common themes of paragon is the deliberate acceptance of risk in order to maintain moral integrity. The 'I won't let fear compromise who I am,' while the Renegade Big Decisions often take a precautionary approach. 'I accept this cost now, because if I don't bigger costs may come later'. Paragon morality was regularly a risk-taker bordering on the irresponsible.
The thing was, though, that the ME trilogy never had those risks materialize. It almost always kicked potential issues far into the future, while Renegade costs were immediate.
I think you've bought into the fantasy a little too heavily, friend.
If you want a game with 'real' consequences to choices, such consequences would come down considerably harder on evil playthroughs than good playthroughs.
As I've said in other threads Mass Effect, like pretty much all video games with choices, is a world with incredibly feeble opposition and nonexistent punishment to outrageous acts of evil. The protagonist is never seriously confronted or hindered no matter how many innocents he gleefully shoots in the face directly in front of people who've made it clear such an act is unforgiveable. The protagonist does what he wants, when he wants, on sheer power of being Just That Totally Badass. At worst, a companion makes a scene only to be smugly and promptly executed and tossed aside.
I don't begrudge video games for doing this. Games are first and foremost about fun, and as I've said many times now, nobody wants to play 'Sit-In-Prison-Simulator' no matter how overwhelmingly appropriate such a response would be.
But let's not go pretending this is what 'real' looks like.