My first ending was Synthesis...... .... .... I think I grieved for several days after that. But I don't think it was a logic-based decision since its pure miasma of space magic. EDI became humanized, all organics became half machine. What are they going to eat? Are the natural world became a part of this schism. And then a lot of reapers are melded dead corpses... imagine one moment you're dying, then the reaper nanites turned your body into a half-machine living corpseand the next you come into consciousness and realized you shared a body with another corpse.... ..... nope. There's a lot of fallacy with Synthesis that I refuse to overthink about it.
Then the control ending...I read Dune series long before I even know what Mass Effect is and Control ending is exactly what Leto has become.... a Machine-God Emperor Shepard isn't what I want.
Refuse is plain stupid but I admire those who insist on it being the real ending.
Destroy is always reasonable to me. Its the only ending that doesn't treat the reapers like a special snowflake. Why would anyone want the reapers to stay? Imagine if your whole family was killed or indoctrinated or turned to husks and then this jackass suddenly decide the reapers are worth saving... I would get sooo pissed..
And so far, Mass Effect series always ended with some form of a huge sacrifice or deaths. The Eden Prime colonists, the Citadel folks who died during the Geth attack. The Protheans who risk their lives to prevent another cycle from happening. The hundreds and thousands of human colonists in the Traverse who was taken and killed by the Collectors. The hundreds and thousands of people at Bahak system (and remember, they kidnap people and make them as slaves. Imagine how many more innocents are killed). Then the reaper war where millions of people were killed and destroyed. But not all synthetics are destroyed. Do you remember that Geth are software intelligence and they can enter into Quarian's suits. Maybe they survive but lose their body, that's why we never see them.